Endocrine Abstracts

Sepsis is defined as “life-threatening organ dysfunction caused by a dysregulated host response to infection”. This response is expressed, inter alia, in the endocrine system and affects almost all endocrine axes. Endocrine dysfunction, in turn, may contribute to other aspects of dysregulated host response to infection, such as metabolism. Endocrine disorders in the course of sepsis are particularly noticeable in the area of the hypothalamic-pituitary-target tissue a...

Introduction: Sepsis is defined as a life-threatening organ dysfunction caused by a dysregulated host response to infection. In sepsis, a phenomenon called obesity paradox has been described, which involves a reduction in mortality in patients with a body mass index allowing for the diagnosis of overweight and obesity. In the clinical context, the phenomenon is confirmed by current meta-analyses. The aim of the study is a systematic review and meta-analysis of studies on obesi...

HAIR-AN is a rarely recognized syndrome which is characterized by hyperandrogenism (HA), insulin resistance (IR) and acanthosis nigricans (AN). In the course of the syndrome, anovulation and metabolic disorders can develop, too. It is therefore suggested by some authors that HAIR-AN is an extreme phenotype of the polycystic ovary syndrome (PCOS). Generally, considering wide spectrum of metabolic and endocrine disorders which can be associated with the syndrome, it still remain...